Chronic Traumatic Encephalopathy (CTE)

A patent pending treatment methodology including bio/pharmaceutical Intervention & Holistic Method's he learned to get his own brain free of CTE

2008 is when my former employer, Novocure, introduced me to Registry Observations and Real World Evidence. Called Optune today, we had an ugly 6 pound medical device that sent 200-khz of alternating electric fields to the supranational region of the brain. I worked at Schering-Plough Oncology seling the only chemotherapy to cross the blood brain barrier, temozolomide to kill Glioblastoma cells as they divided.

Tumor Treating Fields was a joke across the US, to those that didn't understand physics. Over 2.5 years about 680 GBM patients were observed by some of the world's largest Neuro-Oncology leaders. JEREMY RUDNICK, MD & myself can find time June 2 12:30pm PST or June 4 12:30pm PST to go over The Matthew Protocol & graciously accept your grant for $8M to acheive a partial response or complete response in 100 of your former players. I already have the treatment center & world-class facility to fully achieve the best response in 3-months.

Neurology Investigators have boxes to check, drop downs to record total vials/units used, and form-fillable fields are available to add notes. The ease of use and system captures 96% of all patient interactions. HIPAA approved AI will immediately recognize missed visits or incomplete data points. PRC-Forms© automatically saves and allows incomplete data to be saved. 

For CTE patients the electronic form needs to save automatically to account for the unexpected. When a 300-pound lineman with neurological trauma, or a glioblastoma, stands up unexpectedly we won't have time to save the data being entered. PRC Forms© were designed from a doctors perspective and a form half filled out is preferred over an empty one.

Our CRO partner will be notified immediately if data was left incomplete, or if the applicable PRC-Form© was not opened by the end of the expected appointment. The Neurology Investigators research doctor will be emailed, and called, by a member of our Clinical Research Organization. They will determine if the appointment was missed or an IT error occurred. If applicable the missing information can be completed.

A log of when data was entered, and by whom, will be included in the interim and final data analysis for PINR_TMM_RUD-CTE-I© (patent pending). Achieving Fast Track FDA-is approval is critical for the brain health of millions of people that have lost their mind. We cannot risk greedy mistakes so we went straight to the top of our expansive Neuro-Onc Network; Cedars-Sinai hires only the best because they are the best Medical Center in the world, period. 

To achieve 50% partial responders and 20% full responders would be a home run. We aim to do better than that, or there's a 6th treatment modality that may be added to the system or method. One of our chosen 351 biologics manufacturer's may not ship their product in time. It's clear to us that one of the three does not care for true research that they cannot control. The FDA gave them a Drug Master File, maybe in 2021 they used to care about clinical research. We only want to help find a viable treatment for the worst brain injury imaginable. We are prepared with a back-up manufacturer, STAT, who has given us all PCP information as they await for the FDA to accept their own Drug Master File. 

CTE is a devastating, life ruining disease, we have Plan A, Plan B, Plan C, & Plan X all filed for Intellectual Property Protection. There is no guarantee that Plan A will work, @ PINR℠ we think it will. But "data is data" and we need to show that TMM© proves that complete response and partial response are statistically significant. Then the FDA will determine if more research is required, or if we have achieved approval for the 351 Biologics Manufacturer's that have confidence in their product. We will make no outcomes claims and zero non-compliant marketing will be deployed. The Patriot Institute of Neuro-Regeneration℠ & Cedars-Sinai℠ will let the data do all of the talking for us at 1-week, 1-month, 3-month, 6-month endpoints via peer reviewed publications.

Begin the journey to Neurological Recovery

The Patriot Institute of Neurological Regeneration is a Non-Profit Organization who was formed from Patriot Research & Co, LLC (a CA state for-profit LLC). After beginning our research into CTE treatment & generating significant revenue from cash pay high-end former pro athletes. Our CEO kept finding former high level professional athletes who lost all of their money and were practically homeless. That's what CTE will do if left untreated, once proud athletes who made all the right moves since childhood are left making bad business deals, bad investments, getting robbed, getting hooked on drugs, gambling, cheating on their wives, and left broke and broken; with no clue how their celebrity lives fell apart so quickly.

Our upcoming Phase 1/2 Clinical Trial treating CTE with The Matthew CTE Treatment Protocol; will be funded entirely by Grants, Endorsements, Sponsorships, & our private cash reserve. The treatment costs for the (Q4, 2026) opening CTE Trial; (Q1, 2027) Traumatic Brain Injury + Concussion Trial; (Q2, 2027) Alzheimer's Disease Trial, and (Q3, 2027) Stroke-Related Brain Damage clinical trial WILL COST ELIGIBLE PATIENT ZERO Dollars out-of-pocket.

We are your fully staffed, expert, independent research & development pioneer.